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Skin care formulations antimicrobial preservative Polyquaternium-1
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Polyquaternium-1 is also called Polidronium chloride. It is amber to dark brown solid or solution, fairly hygroscopic; bland in taste and nonirritating. Have a large solubility in water, insoluble in ethanol, acetone or ethyl ether. Polyquaternium-1 is no obvious stimulation to the skin, not skin sensitization agent and revulsant, has good antibacterial properties; Polyquaternium-1 can be used as antiseptic for eye-drops as a kind of Ophthalmic preservatives.

  • Product Name: Polyquaternium-1
  • INCI Name: Polyquaternium-1
  • Product Code: YNR®PQ1
  • CAS No.: 75345-27-6
  • Formula: C22H48Cl3N3O6
  • Functions: Ophthalmic preservatives, Antimicrobial preservative

Polyquaternium-1 is a common cosmetic ingredient belonging to the class of polyquaternary ammonium compounds. Polyquaternium-1 is typically used as a preservative and antimicrobial agent, widely applied in eye drops, contact lens solutions, and various skincare products.

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Benefits:

  1. Antimicrobial Preservation: Polyquaternium-1 effectively inhibits the growth of bacteria and fungi, extending the shelf life of products.

  2. Gentleness: Compared to other preservatives, Polyquaternium-1 is less irritating to the skin and eyes, making it suitable for sensitive skin.

  3. Stability: Polyquaternium-1 remains stable across a wide range of pH levels and temperatures, making it versatile for various formulations.

Uses:

  1. Eye Drops and Contact Lens Solutions: Serves as a primary preservative to ensure product sterility.

  2. Skincare Products: Used in creams, lotions, serums, etc., to prevent microbial contamination.

  3. Shampoos and Conditioners: Helps maintain scalp health, preventing dandruff and infections.

Precautions:

  1. Allergic Reactions: Although gentle, a small number of people may still be allergic to it. A patch test is recommended before use.

  2. Concentration Control: High concentrations may cause skin irritation. Polyquaternium-1 should be used at recommended doses.

  3. Pregnant and Nursing Women: Consultation with a doctor is advised to ensure safety.