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Spermidine is a polyamine, meaning it has two or more primary amino groups. It is naturally occurring and is widely encountered in ribosomes and living tissues. It plays a critical role in cell function and survival.
Spermidine can stimulate autophagy. A system that breaks down waste inside cells and recycles cellular components. It is an important quality control mechanism for the mitochondria, the powerhouses of our cells. Autophagy allows damaged or defective mitochondria to be broken down and disposed of. Polyamines can bind to many different types of molecules making them very useful. They support processes, including cell growth, DNA stability, cell proliferation, and apoptosis. It also appears that polyamines function in a similar way to growth factors during cell division.
Spermidine plays an important role in the regulation of various biological processes, including levels of intracellular PH and the maintenance of cell membrane potential. It may delay aging, reduce cognitive decline, reduce the risk of cardiovascular disease. Spermidine has anti-inflammatory properties, so Spermidine can reduce chronic inflammation and may slow down cells and tissues age.
Spermidine is a polyamine compound with the molecular formula C7H19N3. It is a naturally occurring substance widely found in plants, microorganisms, and animal tissues.
In Biological Research, Spermidine is used as a research tool in biological studies to investigate its roles in cell growth, division, and aging processes. Due to its potential health benefits, such as anti-aging and cardiovascular support, Spermidine is often used in nutritional supplements including some dietary supplements. Spermidine is utilized in some skincare and cosmetic products for its antioxidant and moisturizing properties.
The functions of Spermidine:
• Cell Growth and Division: Spermidine plays a crucial role in cell growth and division by participating in DNA replication, mRNA transcription, and protein translation.
• Antioxidant and Anti-aging: It exhibits antioxidant properties, helping to reduce oxidative damage to cells and potentially delaying the aging process.
• To be compared with other flavone plant, Diosmin has it own unique physiologic functions.
• Cardiovascular and Neuroprotective Effects: Studies suggest that spermidine may support cardiovascular health and have neuroprotective effects, potentially reducing the risk of cardiovascular diseases and neurodegenerative conditions.