Featured Products
0102030405
product detail
Polydeoxyribonucleotide (PDRN) is a chemical made up of many (that's the “poly” part of the name) deoxyribonucleotides. Polydeoxyribonucleotide(PDRN) has dual antioxidant properties, and has anti-aging, hydration, soothing in skin care.
PDRN has dual antioxidant properties: it helps thwart oxidative damage from free radicals and, like superstar antioxidant glutathione, can increase skin's supply of its own antioxidants, thus revving up its external defenses. It's also been shown to help repair deeper damage to skin resulting from UV exposure.
Polydeoxyribonucleotide helps to fade hyperpigmentation when combined with vitamin C and niacinamide and delivered to skin via microneedling. Results were compared with using PDRN alone as well as gold standard ingredient hydroquinone, and the PDRN + vitamin C and niacinamide blend was on par with hydroquinone.
Sodium DNA is a signal peptide that mimics extracellular nucleotides. It is composed of DNA fragments from salmon sperm cells. The chemical structure consists of short, low molecular weight DNA chains, ranging from 50 to 1500 kiloDaltons in size. These DNA strands are polymers made up of linked deoxyribonucleotides, which are the building blocks of DNA. The deoxyribonucleotides contain a sugar, phosphate group, and purine or pyrimidine base.
The linear DNA chains twist together into the classic double helix shape. PDRN likely gets broken down by enzymes in the skin into individual nucleotides and nucleosides to provide benefits.
Applications:
Anti-aging: PDRN can remedy the damage to DNA and accelerate the repair of damaged cells by recycling and integrating bases and nucleosides. At the same time, PDRN can also supplement the bases required for DNA synthesis, promote wound healing, and accelerate cell metabolism.
Anti-inflammatory: PDRN can significantly inhibit inflammatory response, reduce symptoms such as redness, swelling, and pain of the skin, and can also inhibit the excessive occurrence of inflammatory response by regulating the expression of inflammatory factors. In addition, PDRN can also promote the production of anti-inflammatory factors and inhibit the release of pro-inflammatory factors.
Anti-oxidation: PDRN also has a certain antioxidant effect, which can effectively remove free radicals, reduce the damage of skin cells by free radicals, delay skin aging, improve skin condition, and prevent endogenous and exogenous aging of the skin.
Repair skin barrier: PDRN can promote the secretion of vascular endothelial growth factor (VEGF) and accelerate the migration, proliferation and angiogenesis of vascular endothelial cells. It can effectively improve the skin's microcirculation, provide more oxygen and nutrients to skin cells, accelerate the repair and regeneration of skin tissue, and promote the repair and reconstruction of the skin barrier.